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Novel approaches for the design and discovery of quorum-sensing inhibitors

✍ Scribed by Scutera, Sara; Zucca, Mario; Savoia, Dianella

Book ID
121863087
Publisher
Informa plc
Year
2014
Tongue
English
Weight
405 KB
Volume
9
Category
Article
ISSN
1746-0441

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Screening for novel quorum-sensing inhib
Screening for novel quorum-sensing inhibitors to interfere with the formation of Pseudomonas aeruginosa biofilm
✍ Ding, X.; Yin, B.; Qian, L.; Zeng, Z.; Yang, Z.; Li, H.; Lu, Y.; Zhou, S. πŸ“‚ Article πŸ“… 2011 πŸ› Society for General Microbiology 🌐 English βš– 742 KB

The objective of this study was to screen for novel quorum-sensing inhibitors (QSIs) from traditional Chinese medicines (TCMs) that inhibit bacterial biofilm formation. Six of 46 active components found in TCMs were identified as putative QSIs based on molecular docking studies. Of these, three comp