✦ LIBER ✦

Novel APP/Aβ mutation K16N produces highly toxic heteromeric Aβ oligomers

✍ Scribed by Daniela Kaden; Anja Harmeier; Christoph Weise; Lisa M. Munter; Veit Althoff; Benjamin R. Rost; Peter W. Hildebrand; Dietmar Schmitz; Michael Schaefer; Rudi Lurz; Sabine Skodda; Raina Yamamoto; Sönke Arlt; Ulrich Finckh; Gerd Multhaup

Book ID: 112083555
Publisher: John Wiley and Sons
Year: 2012
Tongue: English
Weight: 983 KB
Volume: 4
Category: Article
ISSN: 1757-4676
DOI: 10.1002/emmm.201200239

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

A novel mutation in the β-protein coding

A novel mutation in the β-protein coding region of the amyloid β-protein precursor (APP) gene

✍ Milagros Balbín; Magnus Abrahamson; Lars Gustafson; Karin Nilsson; Arne Brun; An 📂 Article 📅 1992 🏛 Springer 🌐 English ⚖ 329 KB

A novel mutation, a C to T transition at base pair 2124 in exon 17 of the amyloid beta-protein precursor (APP) gene, has been identified by direct sequencing of amplified DNA from two Alzheimer's disease (AD) patients. A simple oligonucleotide-hybridization procedure was developed to allow populatio