𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Novel APP mutation V715A associated with presenile Alzheimer’s disease in a German family

✍ Scribed by Marc Cruts; Bart Dermaut; Rosa Rademakers; Marleen Broeck; Florian Stögbauer; Christine Broeckhoven


Publisher
Springer
Year
2003
Tongue
English
Weight
185 KB
Volume
250
Category
Article
ISSN
0340-5354

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


A novel missense mutation (G209R) in exo
✍ Naoya Sugiyama; Kyoko Suzuki; Takehiko Matsumura; Chiaki Kawanishi; Hideki Onish 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 17 KB 👁 2 views

Over fifty missense mutations in the presenilin-1 (PSEN1) gene have been reported in families with presenile familial Alzheimer's disease (FAD). We describe a novel missense mutation (G209R) within the predicted fourth transmembrane domain of the PSEN1 in a Japanese family with presenile FAD. The af

Noninvasive in vivo MRI detection of neu
✍ G. Vanhoutte; I. Dewachter; P. Borghgraef; F. Van Leuven; A. Van der Linden 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 255 KB

## Abstract Transgenic mice overexpressing the London mutant of human amyloid precursor protein (APP[V717I]) in neurons develop amyloid plaques in the brain, thus demonstrating the most prominent neuropathological hallmark of Alzheimer's disease. In vivo 3D __T__~2~\*‐weighted MRI on these mice (24