Novel and Potent 3-(2,3-Dichlorophenyl)-4-(benzyl)-4H-1,2,4-triazole P2X7 Antagonists.
✍ Scribed by William A. Carroll; Douglas M. Kalvin; Arturo Perez-Medrano; Alan S. Florjancic; Ying Wang; Diana L. Donnelly-Roberts; Marian T. Namovic; George Grayson; Prisca Honore; Michael F. Jarvis
- Book ID
- 102006010
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 24 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
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📜 SIMILAR VOLUMES
In the title compound, C~12~H~10~N~8~O~2~S, the triazole and benzene rings make dihedral angles of 72.16 (2) and 7.39 (3)°, respectively, with the thione-substituted triazole ring. In the crystal structure, intermolecular N—H...N hydrogen bonds link the molecules into chains running in the [101] dir
The title compound, C 22 H 18 Cl 2 N 4 , displays the characteristic features of 1,2,4-triazole derivatives. There is an NÐHÁ Á ÁN intermolecular hydrogen bond.
The title compound, C 15 H 13 N 3 S, was prepared by the reaction of 1-(2-chloroethyl)benzene with hydrazine and phenyl isothiocyanate. Packing is stabilized by N-HÁ Á ÁS intermolecular hydrogen bonds and C-HÁ Á Á interactions.