✦ LIBER ✦

Novel aminooxy analogues of spermidine and spermine impair polyamine uptake in Caco-2 cells

✍ Scribed by Turchanowa, Lyudmila; Milovic, Vladan; Khomutov, Alex R.; Khomutov, Radii M.; Caspary, Wolfgang F.; Stein, Juergen

Book ID: 123242954
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 216 KB
Volume: 118
Category: Article
ISSN: 0016-5085
DOI: 10.1016/S0016-5085(00)84236-5

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Insufficiently charged isosteric analogu

Insufficiently charged isosteric analogue of spermine: interaction with polyamine uptake, and effect on Caco-2 cell growth

✍ Lyudmila Turchanowa; Alexander S Shvetsov; Alexander V Demin; Alex R Khomutov; H 📂 Article 📅 2002 🏛 Elsevier Science 🌐 English ⚖ 165 KB

Monitoring of the uptake and metabolism

Monitoring of the uptake and metabolism of aminooxy analogues of polyamines in cultured cells by high-performance liquid chromatography

✍ Tapani Hyvönen; Tuomo A. Keinänen; Alex R. Khomutov; Radii M. Khomutov; Terho O. 📂 Article 📅 1992 🏛 Elsevier Science ⚖ 480 KB

Regulation of spermidine/spermine N1-ace

Regulation of spermidine/spermine N1-acetyltransferase expression by cytokines and polyamines in human hepatocarcinoma cells (HepG2)

✍ M. Alfonsina Desiderio; Giovanna Pogliaghi; Paola Dansi 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 291 KB 👁 2 views

Spermidine/spermine N 1 -acetyltransferase (cSAT), a key enzyme in polyamine degradation, is induced by various hepatotoxins and liver tumor promoters. In this paper we demonstrate that physiological factors, such as cytokines, control cSAT expression in HepG2 human hepatocarcinoma cells. Hepatocyte

Inhibition of cell growth in CaCO2 cells

Inhibition of cell growth in CaCO2 cells by the polyamine analogue N1,N12-bis(ethyl)spermine is preceded by a reduction in MYC oncoprotein levels

✍ Craig M. Berchtold; Pamela Tamez; Thomas W. Kensler; Robert A. Casero Jr. 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 195 KB 👁 1 views

The polyamine analogue N 1 ,N 12 bis(ethyl)spermine (BESpm) is a potent inhibitor of cell proliferation and is representative of a class of agents currently in clinical trials. Previous studies have demonstrated that BESpm treatment can produce a decrease in the mRNA levels of the protooncogene c-my

A 1H/13C inverse 2D method for the analy

A 1H/13C inverse 2D method for the analysis of the polyamines putrescine, spermidine and spermine in cell extracts and biofluids

✍ Wieland Willker; Ulrich Flögel; Dieter Leibfritz 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 239 KB 👁 1 views

The polyamines putrescine, spermidine and spermine are involved in the regulation of various metabolic processes. It is therefore desirable to detect and quantify the polyamines with NMR. We present the proton and carbon assignments for all polyamine signals obtained from PCA extracts of F98 glioma