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Novel alleles in classical major histocompatibility complex class II loci of the brushtail possum (Trichosurus vulpecula)

✍ Scribed by Olivia J. Holland; Phil E. Cowan; Dianne M. Gleeson; Larry W. Chamley

Publisher: Springer-Verlag
Year: 2008
Tongue: English
Weight: 271 KB
Volume: 60
Category: Article
ISSN: 0093-7711
DOI: 10.1007/s00251-008-0300-8

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## Communicated by Henrik Dahl MHC class II deficiency is a severe primary immunodeficiency characterised by the absence of major histocompatibility complex class II (MHC-II) gene expression. It is genetically heterogeneous and can result from defects in at least four different trans-acting regula