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Novel Aerobic Oxidation of Primary Sulfones to Carboxylic Acids

✍ Scribed by Bonaparte, Amy C.; Betush, Matthew P.; Panseri, Bettina M.; Mastarone, Daniel J.; Murphy, Ryan K.; Murphree, S. Shaun


Book ID
111654765
Publisher
American Chemical Society
Year
2011
Tongue
English
Weight
678 KB
Volume
13
Category
Article
ISSN
1523-7060

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A novel CrO~ catalyzed oxidation of primary alcohols to the carboxylic acids is reported. The oxidation proceeds smoothly with only 1-2 tool % of CrO 3 and 2.5 equivalents of H~IO 6 in wet MeCN to give the carboxylic acids in excellent yield. No significant racemization is observed for alcohols with