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Novel actions of bisphosphonates in bone: Preservation of osteoblast and osteocyte viability

✍ Scribed by Teresita Bellido; Lilian I. Plotkin

Book ID: 116323601
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 335 KB
Volume: 49
Category: Article
ISSN: 8756-3282
DOI: 10.1016/j.bone.2010.08.008

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## Abstract It has been proposed that osteocyte viability plays an important role in bone integrity, and that bone loss in osteoporosis may be partially due to osteocyte cell death following estrogen depletion. Osteoporosis treatments such as bisphosphonates can inhibit osteocyte apoptosis which in