Novel 1,3-diol monoethers by a triple tandem aldolization/etherification/Meerwein–Ponndorf–Verley reduction of aliphatic aldehydes

✍ Scribed by Nina Aremo; Tapio Hase

• Book ID: 104230543
• Publisher: Elsevier Science
• Year: 2001
• Tongue: French
• Weight: 62 KB
• Volume: 42
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)00475-0

✦ Synopsis

A one-pot reaction of aliphatic aldehydes with TiCl 4 and Ti(O i Pr) 4 or isopropanol in CH 2 Cl 2 produces dimeric 3-hydroxyethers in moderate yield.