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Novel 12-bp deletion in the coding region of the bovineNPM1gene affects growth traits

โœ Scribed by Y. Z. Huang; E. P. Zhang; H. Chen; J. Wang; Z. J. Li; Y. T. Huai; L. Ma; X. Y. Lan; G. Ren; C. Z. Lei; X. T. Fang; J. Q. Wang

Publisher
Springer-Verlag
Year
2010
Tongue
English
Weight
226 KB
Volume
51
Category
Article
ISSN
1234-1983

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A 12-bp deletion in the 5'-flanking regi
A 12-bp deletion in the 5'-flanking region of the SERPINH1 gene affects promoter activity and protects against preterm premature rupture of membranes in African Americans
โœ Hongyan Wang; Mary D. Sammel; Gerard Tromp; Francesca Gotsch; Indrani Halder; Ma ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 161 KB

We identified a novel 12-bp deletion NT\_033927.7: g.5495364\_5495375del in the 5'-flanking region of the SERPINH1 gene that increases promoter activity. The 12-bp deletion is in linkage disequilibrium with the minor "T" allele of the -656 C/T SNP (NT\_033927.7(SERPINH1):g.5495402C>T) that reduces p