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Notoginseng enhances anti-cancer effect of 5-fluorouracil on human colorectal cancer cells

✍ Scribed by Chong-Zhi Wang; Xiaoji Luo; Bin Zhang; Wen-Xin Song; Ming Ni; Sangeeta Mehendale; Jing-Tian Xie; Han H. Aung; Tong-Chuan He; Chun-Su Yuan

Publisher
Springer
Year
2006
Tongue
English
Weight
506 KB
Volume
60
Category
Article
ISSN
0344-5704

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## Abstract 5‐Fluorouracil (5‐FU) is the major chemotherapeutic component for colorectal cancer (CRC) and other types of solid tumours. Resistance of cancer cells to 5‐FU is considered the major obstacle for successful chemotherapy. NF‐κB is a transcription factor. Cancer cells with high NF‐κB nucl