✦ LIBER ✦
Notoamide E: biosynthetic incorporation into notoamides C and D in cultures of Aspergillus versicolor NRRL 35600
✍ Scribed by Jennifer M. Finefield; Thomas J. Greshock; David H. Sherman; Sachiko Tsukamoto; Robert M. Williams
- Book ID
- 104098990
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- French
- Weight
- 313 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Notoamide E, a short-lived secondary metabolite, has been proposed as a biosynthetic intermediate to several advanced metabolites isolated from Aspergillus versicolor. In order to verify the role of this indole alkaloid along the biosynthetic pathway, synthetic doubly (13)C-labeled notoamide E was fed to Aspergillus versicolor. Analysis of the metabolites showed significant incorporation of notoamide E into the natural products notoamides C and D.