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Notiz zur DarstellungN,N-disubstituierter aliphatischer Thiocarbonsäureamide,N-substituierter Thiolactame und aromatischer Thiocarbonsäureester

✍ Scribed by Kantlehner, Willi ;Haug, Erwin ;Farkas, Michael


Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
308 KB
Volume
1982
Category
Article
ISSN
0947-3440

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✦ Synopsis


Note on the Preparation of N,N‐Disubstituted Aliphatic Thiocarboxamides, N‐Substituted Thiolactams, and Aromatic Thiocarboxylates

Hydrogen sulfide reacts with the N,N‐dimethylformamide acetal 1 to give N,N‐(dimethyl)thioformamide (2a). The thioamides 2a–e and the thiolactams 2f, g are prepared by thiolysis of the nitriles 3a–g. The action of hydrogen sulfide on nitriles 5a–f affords the O‐ethyl thiocarboxylates 6a–f. The preparation of the nitriles 3g and 5a–f is described.