Polyamine-dependent alterations in the s
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Jyrki J. Parkkinen; Mikko J. Lammi; Ulla Γ
gren; Markku Tammi; Tuomo A. KeinΓ€nen;
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Article
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1997
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John Wiley and Sons
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English
β 277 KB
π 2 views
The activity of ornithine decarboxylase, the key enzyme in the synthesis of polyamines, is essential for proliferation and differentiation of all living cells. Two inhibitors of ornithine decarboxylase, a-difluoromethylornithine (DFMO) and 1-aminooxy-3-aminopropane (APA), caused swelling of endoplas