## Abstract A case of advanced diabetic microvascular disease secondary to impaired glucose tolerance (IGT) with server proliferative retinopathy, end‐stage diabetic nephropathy and chronic peripheral neuropathy is described. There was concomitant large vessel disease with Fournier's gangrene and l
Notes designed as an aid to professional education. A very unusual case of hyperosmolar coma
✍ Scribed by Lewis, MJ ;Ferguson, SC ;Campbell, IW ;Nawroz, IM
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 393 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1357-8170
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Hyperglycaemic coma without ketoacidosis in the diabetic patient was presumptively first recorded by Dreschfield in 1886^1^ but it was not until 1957 that the concept of hyperosmolar non‐ketotic coma as a distinct clinical syndrome was appreciated^2,3^. Hyperosmolar non‐ketotic coma (HONK) occurs typically in the elderly diabetic subject. Up to 60% of diabetic patients with HONK have previously undiagnosed diabetes mellitus. In these elderly patients, there are often multiple precipitating factors with infection being the most common^4^. We present the case of a female with HONK and an unusual infection, the combination of which led to her sudden and unexpected death.
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