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Normal V(D)J recombination in cells from patients with Nijmegen breakage syndrome

โœ Scribed by Eva Harfst; Suzanne Cooper; Susann Neubauer; Luitpold Distel; Ulf Grawunder

Book ID
117325287
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
585 KB
Volume
37
Category
Article
ISSN
0161-5890

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## Abstract Nijmegen breakage syndrome (NBS) patients and carriers are predisposed to malignancy and are often treated with Xโ€irradiation. In the present study, the singleโ€cell gel electrophoresis (Comet) assay was used to examine radiationโ€induced DNA damage and repair in peripheral blood mononucl