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Normal striatal glucose consumption in two patients with benign hereditary chorea as measured by positron emission tomography

✍ Scribed by T. Kuwert; H. W. Lange; K. -J. Langen; H. Herzog; H. Hefter; A. Aulich; L. E. Feinendegen

Publisher: Springer
Year: 1990
Tongue: English
Weight: 951 KB
Volume: 237
Category: Article
ISSN: 0340-5354
DOI: 10.1007/bf00314666

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✦ Synopsis

Positron emission tomography (PET) with [18F]-2-fluoro-2-deoxy-D-glucose (FDG) was used to investigate the regional cerebral metabolic rate of glucose consumption (rCMRGlc) in two patients with benign hereditary chorea (BHC) and 21 normal subjects. Relative and absolute values of cerebellar, striatal, thalamic, and cortical rCMRGlc were within normal limits for both patients with BHC, indicating that the choreic movement disorder encountered in these two patients was not caused by a decrease of energy metabolism in the striatum such as that found regularly in most patients with other forms of chorea (e.g. Huntington's and Wilson's disease).

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