𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Normal immunosuppressive protein inhibition of human and murine lymphoblastoid cell line proliferation

✍ Scribed by David Nelken; Haim Ovadia; Nabil Hanna

Book ID
102160000
Publisher
John Wiley and Sons
Year
1979
Tongue
English
Weight
158 KB
Volume
9
Category
Article
ISSN
0014-2980

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✦ Synopsis

Abstract

Normal immunosuppressive protein, prepared from human plasma by DEAE‐cellulose chromatography, inhibits DNA synthesis in human cell lines of lymphocytes of both T and B origin. It also inhibits [^3^H]thymidine incorporation in mouse cell lines. Normal immunosuppressive protein was able to inhibit the proliferation of these cells, although they were already transformed and had a high rate of DNA synthesis. On the other hand, it does not inhibit myeloid cells or fibroblasts.

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