Normal human plasma contains antibodies that specifically block neuropathy-associated human anti-GM1 IgG-antibodies

Anti-GM1 ganglioside igm-antibodies pres

Anti-GM1 ganglioside igm-antibodies present in human plasma: Affinity and biological activity changes in a patient with neuropathy

✍ Roxana K. Mizutamari; Leonardo J. Kremer; Elizabeth A. Basile; Gustavo A. Nores 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 93 KB 👁 1 views

Low affinity anti-GM 1 IgM-antibodies are part of the normal repertoire of human plasma antibodies (Mizutamari et al.: J Neuroimmunol 50:215-220, 1994), a fact that is against the pathological role proposed for them in autoimmune diseases. Here we present evidence that these low affinity IgM-antibod