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Normal DNA polymorphism at the low density lipoprotein receptor (LDLR) locus associated with serum cholesterol level

✍ Scribed by Jan Chr. Pedersen; Káre Berg


Book ID
115089744
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
446 KB
Volume
34
Category
Article
ISSN
0009-9163

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✍ X.L. Wang; R. Badenhop; K.E. Humphrey; D.E.L. Wilcken 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 622 KB

We recently showed that loss of a MspI restriction site in the 5'-end (intron 1) of the apolipoprotein (apo) AI gene is due to a C to T transition (+83 bp) and/or a G to A transition (+84 bp). Since this region may be relevant to the regulation of apo AI gene expression and therefore to plasma high