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Normal cerebrospinal fluid suppresses the in vitro development of cytotoxic T cells: Role of the brain microenvironment in CNS immune regulation

✍ Scribed by Leslie B Gordon; Scott C Nolan; Bruce R Ksander; Paul M Knopf; Christine J Harling-Berg


Book ID
117337730
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
96 KB
Volume
88
Category
Article
ISSN
0165-5728

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## Abstract Apoptosis is an important mechanism enabling the selection of the non‐self‐reactive T cell repertoire and for maintaining homeostasis in the immune system after it has expanded to combat infections. Highly activated, proliferating T cells become susceptible to apoptosis driven by a numb