Normal Breast Epithelial Cells Induce Apoptosis of Breast Cancer Cells via Fas Signaling
✍ Scribed by Robert-Alain Toillon; Simon Descamps; Eric Adriaenssens; Jean-Marc Ricort; David Bernard; Bénoni Boilly; Xuefen Le Bourhis
- Book ID
- 115604249
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 344 KB
- Volume
- 275
- Category
- Article
- ISSN
- 0014-4827
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Fas (CD95/Apo-1) is a cell membrane receptor that upon binding by its ligand (FasL), triggers a signal resulting in apoptotic cell death. Fas is produced by breast epithelial cells, but its contribution to breast tissue homeostasis is unknown. This study investigated whether FasL is synthesized in t