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Normal and pathological bone development controlled by the AP-1 transcription factor complex

โœ Scribed by EF Wagner


Book ID
120707804
Publisher
BioMed Central
Year
2001
Tongue
English
Weight
430 KB
Volume
3
Category
Article
ISSN
1478-6354

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p53 down-regulates matrix metalloprotein
โœ Yubo Sun; Xiao-Rong Zeng; Leonor Wenger; Gary S. Firestein; Herman S. Cheung ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 276 KB

## Abstract We have previously reported that human matrix metalloproteinaseโ€1 (MMP1) is a __p53__ target gene subject to downโ€regulation (Sun et al. [1999]: J Biol Chem 274:11535โ€“11540]. In the present study, we demonstrate that the downโ€regulation of the human โˆ’83MMP1 promoter fragment by p53 was