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Normal and Malignant Cell Growth

✍ Scribed by Leonard F. Lamerton (auth.), R. J. Michael Fry, M. L. Griem, W. H. Kirsten (eds.)


Publisher
Springer-Verlag Berlin Heidelberg
Year
1969
Tongue
English
Leaves
246
Series
Recent Results in Cancer Research / Fortschritte der Krebsforschung / Progrès dans les recherches sur le cancer 17
Edition
1
Category
Library

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✦ Synopsis


This volume presents the Proceedings of the University of Chicago's third Cancer Training Grant supported Teaching Symposium. This Symposium received much of its support from grant number T12 CA 08077-02. Most of the planning of the Symposium and most of the local editing of the Proceedings was carried out by Dr. R. J. Michael Fry of the A.E.C. Argonne National Laboratory and by two members of the Advisory Committee of the Cancer Training Grant, Drs. Melvin Griem and Werner Kirsten. They carried the main responsibility for the Symposium. The subject of the Symposium, "Normal and Malignant Cell Growth," was chosen because, as the Proceedings reflect, it is a rapidly advancing field of endeavor which is of utmost importance to the understanding of the processes of malignant neoplasia. In fact, there is increasing evidence that knowledge of the kinetics of the cancer cell will greatly influence approaches to cancer therapy. Like the first two of these Teaching Symposia held in 1964 and 1966, this one attracted about 400 students and staff from this medical institution as well as from other medical centers in the Chicago area. The effective interplay of an excellent group of scientists with a lively and responsive audience was evident as they considered together a topic of great current interest in the field of neoplasia. Much of the credit for the smooth organization and implementation of the Symposium must go to Mrs.

✦ Table of Contents


Front Matter....Pages i-xv
General Introduction....Pages 1-9
Proliferative Capacity of Hemopoietic Stem Cells....Pages 10-20
Discussion Colony Forming Units in the Bone Marrow of Partial Body Irradiated Mice....Pages 21-27
Cellular Proliferation in the Liver....Pages 28-43
Discussion Cellular Proliferation in the Liver....Pages 43-48
Cell Proliferation in the Intestinal Epithelium....Pages 49-56
Discussion Proliferation of Gastrointestinal Cells....Pages 56-59
Proliferation of Antibody-Forming Cells....Pages 66-75
Discussion The Proliferation of Antibody-Forming Cells....Pages 75-78
Composition of the Cell Life Cycle....Pages 79-90
Discussion Methods and Criteria of Mammalian Cell Synchrony....Pages 90-103
Susceptibility of Intestinal Crypt Epithelium to Hydroxyurea and Other Antitumor Agents....Pages 104-108
Discussion Mammalian Cell Killing by Inhibitors of DNA Synthesis....Pages 109-117
The Growth of Tumor Cells Under Normal and Fasting Conditions....Pages 118-127
Cell Proliferation during Carcinogenesis....Pages 128-135
Comparison Between the Rates of Proliferation of Induced Malignancies and Their Normal Tissues of Origin....Pages 136-146
The Use of Three-Dimensional Matrix Tissue Culture for Bioassay of Cancer: A Progress Report....Pages 147-163
Discussion The Use of Three-Dimensional Matrix Tissue Culture for Bioassay of Cancer....Pages 163-167
Importance of the Non-Dividing Leukemic Cell....Pages 168-174
Discussion Magnitude of Proliferating Fraction and Rate of Proliferation of Populations of Leukemic Cells in Man....Pages 175-185
Incorporation of 125 Iodine-Labeled 5-Iodo-2β€²-Deoxyuridine into the DNA of Mouse Mammary Tumors....Pages 186-201
In Vivo Cell Kinetics of Human Cancers....Pages 202-217
Summary of Symposium on Normal and Malignant Cell Growth....Pages 218-225
Back Matter....Pages 226-236

✦ Subjects


Medicine/Public Health, general


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