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Normal and induced synthesis of δ-aminolevulinic acid synthetase in developing chick liver

✍ Scribed by Simons, J. A. ;Boell, E. J.

Publisher
John Wiley and Sons
Year
1971
Tongue
English
Weight
376 KB
Volume
178
Category
Article
ISSN
0022-104X

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✦ Synopsis

GAminolevulinic acid synthetase activity in embryonic chick liver is not detectable until just before hatching when i t surges to more than four times the adult level (12 moles ALAlg liver/h) which is reached in the first week after hatching. An injection of 3,5-dicarbethoxy-l,4-dihydrocollidine into the egg results in a massive increase in the activity of the enzyme-up to 40 times the adult level. In addition, the enzyme can also be induced in embryonic chick liver by hypoxia.

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