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Norharman inhibition of [3H]-diazepam binding in mouse brain

✍ Scribed by Anne M. Morin; Iris A. Tanaka; Claude G. Wasterlain


Book ID
118940610
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
316 KB
Volume
28
Category
Article
ISSN
0024-3205

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Several purines have been shown to be competitive inhibitors of [3H] diazepam binding. Inosine has also been shown to have benzodiazepine-like neurophysiologic, pharmacologic and behavioral effects, and to partially inhibit caffeine-induced seizures in mice. Using presumptive therapeutic doses ofino