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Norfloxacin prevents spontaneous bacterial peritonitis (SBP) in cirrhosis. Final results of a multicenter double-blind placebo controled study

✍ Scribed by Ginès, P; Rimola, A; Planas, R; Vargas, V; Forné, M; Miranda, ML; Rodrigo, L; del Val, A; Marco, F; Almela, H


Book ID
122727340
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
107 KB
Volume
11
Category
Article
ISSN
0168-8278

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Norfloxacin prevents spontaneous bacteri
✍ Dr. Pere Ginés; Antoni Rimola; Ramón Planas; Victor Vargas; Francesc Marco; Manu 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 958 KB

Eighty cirrhotic patients who had recovered from an episode of spontaneous bacterial peritonitis were included in a multicenter, double-blind trial aimed at comparing long-term norfloxacin administration (400 mglday; 40 patients) vs. placebo (40 patients) in the prevention of spontaneous bacterial p

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Cefotaxime (CTX) is considered one of the first-choice antibiotics in the therapy of spontaneous bacterial peritonitis (SBP) in cirrhosis. Because CTX is largely metabolized in the liver, this drug may also be effective in SBP by administering lower doses than those habitually used. To investigate t