Targeted disruption of Nemo-like kinase
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Kwang Hwa Jung; Jeong Kyu Kim; Ji Heon Noh; Jung Woo Eun; Hyun Jin Bae; Hong Jia
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Article
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2010
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John Wiley and Sons
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English
β 504 KB
## Abstract The Wnt/Ξ²βcatenin signaling pathway regulates various aspects of development and plays important role in human carcinogenesis. Nemoβlike kinase (NLK), which is mediator of Wnt/Ξ²βcatenin signaling pathway, phosphorylates Tβcell factor/lymphoid enhancer factor (TCF/LEF) factor and inhibit