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Noradrenoceptor antagonism with idazoxan improvesl-dopa-induced dyskinesias in MPTP monkeys

✍ Scribed by R. Grondin; Abdallah Hadj Tahar; Van Diep Doan; P. Ladure; P.J. Bédard


Book ID
105878552
Publisher
Springer-Verlag
Year
2000
Tongue
English
Weight
134 KB
Volume
361
Category
Article
ISSN
0028-1298

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## Abstract Levodopa‐induced dyskinesias (LIDs) are frequent in parkinsonian patients and may result from an aberrant plasticity. Brain‐derived neurotrophic factor (BDNF) represents a likely candidate to subserve neuroadaptive processes encountered in LIDs. We compared striatal BDNF levels measured