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Noonan's syndrome and coagulation-factor deficiencies

✍ Scribed by Emmerich, Joseph; Aiach, Martine; Capron, Loïc; Noël Fiessinger, Jean


Book ID
122279347
Publisher
The Lancet
Year
1992
Tongue
English
Weight
180 KB
Volume
339
Category
Article
ISSN
0140-6736

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Isolated Factor V and X deficiencies were associated with acute leukemia in 2 patients. Both patients manifested a hemorrhagic diathesis. In the patient with Factor V deficiency, the level of Factor V was related to the activity of his leukemia. The mechanism of these deficiencies is unclear, but th