Mark A. Findeis and a panel of active researchers present their best methods not only for preparing, handling, and characterizing gene delivery agents, but also for gene delivery. To help those preparing and characterizing gene transfer agents, the contributors examine a broad range of compounds tha
Nonviral Vectors for Gene Therapy: Methods and Protocols (Methods in Molecular Medicine)
โ Scribed by Mark A. Findeis
- Year
- 2001
- Tongue
- English
- Leaves
- 413
- Edition
- 1
- Category
- Library
No coin nor oath required. For personal study only.
โฆ Synopsis
Mark A. Findeis and a panel of active researchers present their best methods not only for preparing, handling, and characterizing gene delivery agents, but also for gene delivery. To help those preparing and characterizing gene transfer agents, the contributors examine a broad range of compounds that bind with DNA to form the compact condensed phases that facilitate cellular delivery-among them peptide conjugates, synthetic polymers, and lipids. They also outline specific approaches to gene transfer in vivo, including direct delivery by intratumoral injection and indirect delivery by cell-specific targeting of DNA complexes, and discuss in detail many spectroscopic techniques for characterizing nonviral gene delivery agents.
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<span>The purpose of this volume of Methods in Molecular Medicine is to set forth examples of the great variety of techniques and applications that are now emerging in the field of nonviral gene therapy. The book emphasizes not only specific approaches to gene delivery but, in particular, the best c
Oregon Health & Science Univ., Portland, OR. Text provides basic tools needed for design targeted gene delivery vectors, and an understanding of how to apply viral vectors to the treatment of genetic disorders. Includes step-by-step methods, vectors from major categories, guidance on the selection,
Oregon Health & Science Univ., Portland, OR. Text provides basic tools needed for design targeted gene delivery vectors, and an understanding of how to apply viral vectors to the treatment of genetic disorders. Includes step-by-step methods, vectors from major categories, guidance on the selection,
Mark A. Findeis and a panel of active researchers present their best methods not only for preparing, handling, and characterizing gene delivery agents, but also for gene delivery. To help those preparing and characterizing gene transfer agents, the contributors examine a broad range of compounds tha