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Nonsyndromic X-linked mental retardation: where are the missing mutations?

✍ Scribed by Hans-Hilger Ropers; Maria Hoeltzenbein; Vera Kalscheuer; Helger Yntema; Ben Hamel; Jean-Pierre Fryns; Jamel Chelly; Michael Partington; Jozef Gecz; Claude Moraine


Book ID
114173491
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
123 KB
Volume
19
Category
Article
ISSN
0168-9525

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Nonsyndromic X-linked mental retardation
✍ Holinski-Feder, Elke; Chahrockh-Zadeh, Soheyla; Rittinger, Olaf; Jedele, Kerry B πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 27 KB πŸ‘ 2 views

An Austrian family with nonsyndromic Xlinked mental retardation (MRX) is reported in which the obligatory carrier females are normal, and 5 affected males have mild to moderate mental retardation. Linkage analysis indicated an X pericentromeric localization, with flanking markers DXS989 and DXS1111