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Nonsteroidal anti-inflammatory drugs alter body temperature and suppress melatonin in humans

โœ Scribed by Patricia J. Murphy; Bryan L. Myers; Pietro Badia


Book ID
116046917
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
646 KB
Volume
59
Category
Article
ISSN
0031-9384

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Disposition of CS-670, a novel nonsteroi
โœ Masato Asami; Akemi Shigeta; Yorihisa Tanaka ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 588 KB

CS-670, a novel nonsteroidal anti-inflammatory drug, is a racemic prodrug. Plasma concentrations and urinary excretion of CS-670 and its metabolites were determined in experimental subjects after oral administration at a single 120 mg dose. CS-670 and four metabolites, the saturated ketone (M-A), un