The little (lit) mutation cosegregates w
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Streamson C. Chua; Karen Hennessey; Phillip Zeitler; Rudolph L. Leibel
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Article
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1993
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Springer-Verlag
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English
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The little (lit) autosomal recessive mutation in the mouse causes dwarfism due to isolated growth hormone deficiency. The in vitro physiology of pituitary growth hormone release in lit~lit animals suggests that an abnormality in the growth hormone releasing factor (GRF) receptor (Ghrfr) is a very li