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Nonrigid registration of multiple sclerosis brain images using lesion inpainting for morphometry or lesion mapping

✍ Scribed by Michaël Sdika; Daniel Pelletier


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
280 KB
Volume
30
Category
Article
ISSN
1065-9471

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✦ Synopsis


Abstract

Morphometric studies of medical images often include a nonrigid registration step from a subject to a common reference. The presence of white matter multiple sclerosis lesions will distort and bias the output of the registration. In this article, we present a method to remove this bias by filling such lesions to make the brain look like a healthy brain before the registration. We finally propose a dedicated method to fill the lesions and present numerical results showing that our method outperforms current state of the art method. Hum Brain Mapp, 2009. © 2008 Wiley‐Liss, Inc.