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Nonrandom distribution of receptors for melanocyte-stimulating hormone on the surface of mouse melanoma cells

✍ Scribed by Varga, Janos M. ;Saper, Mark A. ;Lerner, Aaron B. ;Fritsch, Peter


Publisher
Wiley (John Wiley & Sons)
Year
1976
Tongue
English
Weight
316 KB
Volume
4
Category
Article
ISSN
0091-7419

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✦ Synopsis


Abstract

An improved bubble method was developed for applying an ultrathin layer of nuclear track emulsion on the surface of cells labeled with I^125^‐MSH. The autoradiographs of I^125^‐MSH binding indicate a nonrandom distribution of receptors on the surface of mouse melanoma cells. It is suggested that MSH receptors are displayed in clusters previous to an independently of their exposure to the hormone.