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Nonrandom changes of chromosome 10 in bladder cancer: Detection by FISH to interphase nuclei

✍ Scribed by Ming-Rong Wang; Bernard Perissel; Jacques Taillandier; Jean-Louis Kémény; Yvette Fonck; André Lautier; Moncef Benkhalifa; Paul Malet


Book ID
119106176
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
821 KB
Volume
73
Category
Article
ISSN
0165-4608

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Two genes (arylamine N-acetyltransferase types 1 and 2, NAT1 and NAT2), which are known to metabolize bladder carcinogens, are located on chromosome band 8p22. Alterations in chromosome 8, including deletions of 8p, occur frequently in many epithelium-derived tumors. In this study, fluorescence in s