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Nonphorbol tumor promoters okadaic acid and calyculin-A induce membrane translocation of protein kinase C

โœ Scribed by Rayudu Gopalakrishna; Zhen H. Chen; Usha Gundimeda


Book ID
115765743
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
602 KB
Volume
189
Category
Article
ISSN
0006-291X

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We have reported that treatment with okadaic acid, a potent protein phosphatase inhibitor, has the ability to enhance the synthesis of the 78-kDa glucose-regulated protein (GRP78). This article reports our investigation of another protein phosphatase inhibitor, calyculin A, demonstrating the signali