Physicochemical and biopharmaceutical ch
โ
Andrea Cappelli; Valter Travagli; Iacopo Zanardi; Maurizio Anzini; Gianluca Gior
๐
Article
๐
2006
๐
John Wiley and Sons
๐
English
โ 422 KB
The physicochemical and biopharmaceutical properties, such as pK a , crystal habit, water solubility, logD, molecular structure and dynamics, and membrane permeability of CR3124 (endo-2-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2,3-dihydro-1Hbenz[e]isoindol-1-one, a novel potent 5-HT 3 receptor antagon