Although previous association studies have demonstrated that the APOE4 allele is a risk factor for Alzheimer's disease (AD), its value for the prediction of AD in individuals is <100%. The limited predictive value of β4 is also seen in multiply affected families where the β4 allele is not tightly li
Nonparametric Linkage does not provide strong evidence for linkage to APOE in a large alzheimer's kindred
β Scribed by Paterson, Andrew D. ;Kennedy, James L.
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 2 KB
- Volume
- 81
- Category
- Article
- ISSN
- 0148-7299
- DOI
- 10.1002/(sici)1096-8628(19980508)81:3<268::aid-ajmg11>3.0.co;2-d
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Once upon a time, someone in your family knew why all the strange occurrences and coincidences are so prevalent.Β Some stories are still whispered from Grandmother to Granddaughter. Β Tales of how a Great-Aunt could find children lost in the woods at the edge of town. Β Rumors of an ancestor who could