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Nonosseous sarcomas in a military hospital

✍ Scribed by Dr. Timothy R. Shaver; Yeu-Tsu Margaret Lee


Book ID
102925016
Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
524 KB
Volume
36
Category
Article
ISSN
0022-4790

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✦ Synopsis


This is a retrospective review of 67 patients with soft tissue or visceral sarcomas treated during [1973][1974][1975][1976][1977][1978][1979][1980][1981][1982]. There were 40 males and 27 females. The mean age was 36 with a range of 1 to 77 years of age. The most common histologic subtypes were rhabdomyosarcoma (19 %) , malignant fibrohistiocytoma (13 %), fibrosarcoma, leiomyosarcoma, dermatofibrosarcoma protuberans (12 % each), and liposarcoma (10 %). Among the 42 soft tissue sarcomas 33% occurred in the trunk, 35 % and 21 % in the lower and upper extremities, and 10% in the head and neck region. Among the 25 visceral sarcomas, 16% were in the thorax, 56% involved abdominal or retroperitoneal organs, and 28% were in the head and neck region. Overall, 33 of the 54 patients with early sarcomas were treated by surgical resection alone while 21 others had postoperative adjuvant radiotherapy and/or chemotherapy. Factors influencing survival are presented and patterns of metastasis discussed. Overall, 45% of the patients showed metastatic disease either at diagnosis (15%) or duirng the follow-up period (30%). The lung was involved in two-thirds of the cases and was the most common site of spread. In patients with rhabdomyosarcoma and malignant fibrohistiocytoma, regional lymph node metastasis was noted in 36% and 17 % , respectively.


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