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Nonneoplastic circulating sézary-like cells in cutaneous T-cell lymphoma. Ultrastructural, immunologic, and T-cell receptor gene-rearrangement studies

✍ Scribed by Albert Bendelac; Nigel Tj O'Connor; Marie-Thérèse Daniel; Christian Boitard; Catherine Michel; Liliane Laroche; Philippe Lesavre; Jean-François Bach


Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
835 KB
Volume
60
Category
Article
ISSN
0008-543X

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## Detection of clonal T-cell receptor (TCR )-chain gene rearrangement is a promising approach to distinguish between cutaneous T-cell lymphomas (CTCLs) and reactive T-cell infiltrates. Despite the improved sensitivity by using the polymerase chain reaction (PCR) rather than Southern blot analysis