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Nonlinear relationship between plasma and red blood cell pharmacokinetics of chlorthalidone in man

✍ Scribed by Harry L. J. Fleuren; Jacques M. van Rossum


Book ID
112473365
Publisher
Springer
Year
1977
Tongue
English
Weight
859 KB
Volume
5
Category
Article
ISSN
1573-8744

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Plasma and red blood cell pharmacokineti
✍ K. -M. Chu; S. -M. Shieh; O. Y. -P. Hu πŸ“‚ Article πŸ“… 1995 πŸ› Springer 🌐 English βš– 630 KB

The pharmacokinetics of enantiomers of pimobendan and their demethylated metabolites in plasma and red cells were studied in 8 normal healthy volunteers. After racemic pimobendan 5 mg IV, the plasma concentration-time curve followed a two-compartment open-model with elimination half-lives of 1.81 h