✦ LIBER ✦

Nonlinear laser imaging of skin lesions

✍ Scribed by R. Cicchi; S. Sestini; V. De Giorgi; D. Massi; T. Lotti; F. S. Pavone

Book ID: 102294044
Publisher: John Wiley and Sons
Year: 2008
Tongue: English
Weight: 464 KB
Volume: 1
Category: Article
ISSN: 1864-063X
DOI: 10.1002/jbio.200710003

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

We investigated different kinds of human ex‐vivo skin samples by combined two‐photon intrinsic fluorescence (TPE), second‐harmonic generation microscopy (SHG), fluorescence lifetime imaging microscopy (FLIM), and multispectral two‐photon emission detection (MTPE). Morphological and spectroscopic differences were found between healthy and pathological skin samples, including tumors. In particular, we examined tissue samples from normal and pathological scar tissue (keloid), and skin tumors, including basal cell carcinoma (BCC), and malignant melanoma (MM). By using combined TPE‐SHG microscopy we investigated morphological features of different skin regions. Further comparative analysis of healthy skin and neoplastic samples was performed using FLIM, and MTPE. Finally, we demonstrated the use of methyl‐aminolevulinate as a contrast agent to increase the contrast in BCC border detection. The results obtained represent further support for in‐vivo noninvasive imaging of diseased skin. (© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)

📜 SIMILAR VOLUMES

Skin capacitance imaging of acne lesions

✍ Emmanuelle Xhauflaire-Uhoda; Gérald E. Piérard 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 266 KB

Erbium:YAG Laser Therapy of Skin Lesions

✍ Roland Kaufmann; Christian Beier 📂 Article 📅 2001 🏛 Elsevier Science 🌐 English ⚖ 514 KB

Assessment of melanocytic skin lesions w

Assessment of melanocytic skin lesions with a high-definition laser Doppler imaging system

✍ Robert E. Hunger; Rocco Della Torre; Alexandre Serov; Thomas Hunziker 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 288 KB

Ruby laser treatment of pigmented skin l

Ruby laser treatment of pigmented skin lesions

✍ Takeshi Shimbashi; Tadao Kojima 📂 Article 📅 1995 🏛 Springer 🌐 English ⚖ 425 KB

Pigmented skin lesions were treated by a ruby laser with a wavelength of 694 nm and a pulse duration of 450 txs. The clinical result of laser treatment was good in 18 of the 55 cases (32%). Five of 21 cases (23.8%) with cafe-au-lait maculae, 9 of the 14 cases (64%) with senile pigmentation, and 3 of

Laser treatment of skin lesions in child

Laser treatment of skin lesions in children

✍ Manjeet Mehmi; Sean W. Lanigan 📂 Article 📅 2007 🏛 Medicine Publishing Company Ltd 🌐 English ⚖ 728 KB

Automatic registration of images of pigm

Automatic registration of images of pigmented skin lesions

✍ Bruce Mcgregor 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 397 KB

Melanoma rates in whites are increasing rapidly. Early detection, primarily through altered appearance of pigmented skin lesions, is the strongest determinant of survival. For high-risk patients photographic records are invaluable, but images must first be ''registered'' to remove distortions introd