✦ LIBER ✦

Nonlinear compartmental model indistinguishability

✍ Scribed by M.J. Chapman; K.R. Godfrey

Book ID: 102640357
Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 473 KB
Volume: 32
Category: Article
ISSN: 0005-1098
DOI: 10.1016/0005-1098(95)00152-2

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✦ Synopsis

version of the local state isomorphism theorem is used to show how nonlinear model structures, within some specified class, can be tested for indistinguishability from some given structure via a suitable choice of their respective parameters. This theory is applied to a two-compartmental structure with an assumed Michaelis-Menten elimination from compartment 1. Models tested for indistinguishability include structures with Michaelis-Menten elimination from compartment 2 in addition to, or instead of, that from compartment 1.

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