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Nonisotopic receptor-binding assay for benzodiazepine receptors utilizing a fluorophore labeled ligand

โœ Scribed by Toshifumi Takeuchi; Garry A. Rechnitz

Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
653 KB
Volume
194
Category
Article
ISSN
0003-2697

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โœฆ Synopsis

A nonisotopic receptor-binding assay method provides a new approach for the study of receptor-ligand interactions and a possible receptor assay for benzodiazepine drugs. The proposed method is based upon the use of fluorescence-labeled drugs and a chromatographic system which accepts samples without deproteinization. The effectiveness of the technique is illustrated in a study of benzodiazepine receptor-drug-binding interactions.

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