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Noninvasive detection of Alzheimer's disease Aβ pathology in the lenses of human subjects with Down syndrome

✍ Scribed by Juliet Moncaster; Srikant Sarangi; Olga Minaeva; Noel Casey; Robert Webb; Danielle Ledoux; John Clark; David Hunter; Lee Goldstein

Book ID: 118468524
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 67 KB
Volume: 8
Category: Article
ISSN: 1552-5260
DOI: 10.1016/j.jalz.2012.05.591

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## Abstract ## Objectives To investigate the relation of plasma levels of A__β__ peptides (A__β__1‐40 and A__β__1‐42) and apolipoprotein E (APOE) genotype to dementia status, and the duration of Alzheimer's disease (AD) in adults with Down syndrome (DS). ## Methods Adults with DS were recruited