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Noninvasive approach to the assessment of activity of the hypothalamic-pituitary adrenal system of the Amur tigers

✍ Scribed by V. V. Rozhnov; V. S. Lukarevskiy; H. A. Hernandez-Blanco; P. A. Sorokin; M. N. Litvinov; A. K. Kotlyar; V. G. Udin; S. V. Naydenko

Book ID
110159702
Publisher
Springer
Year
2010
Tongue
English
Weight
107 KB
Volume
430
Category
Article
ISSN
0012-4966

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Many patients with major depression show evidence of over-activation of the hypothalamic - pituitary - adrenal axis (HPA), as evidenced by hypercortisolism and adrenal hyperplasia. Such over-activity is associated with increased corticotropin releasing factor (CRF) reactivity in the CSF and blunted