Recent studies indicate that the vitamin D hormone, 1 a,25-dihydroxyvitamin D3 exerts rapid effects (seconds to minutes) in a variety of cell types. These rapid nongenomic actions in osteoblasts include effects on membrane voltage-gated calcium channels, phospholipase C activity, and the sodium/hydr
✦ LIBER ✦
Nongenomic Effects of 1α,25-Dihydroxyvitamin D3
✍ Scribed by Alberto Revelli; Marco Massobrio; Jan Tesarik
- Book ID
- 117700496
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 200 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1043-2760
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## Abstract For Abstract see ChemInform Abstract in Full Text.
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In this communication we describe the synthesis of \(1 \alpha, 25\)-dihydroxyvitamin \(\mathrm{D}_{3}\) - \(3 \beta\)-bromoacetate \(\left[1,25(\mathrm{OH})_{2}-\mathrm{BE}\right]\), an analog of \(1 \alpha, 25\)-dihydroxyvitamin \(\mathrm{D}_{3}\left[1,25(\mathrm{OH})_{2} \mathrm{D}_{3}\right]\), a
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