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Nongenetic causes of hearing loss

✍ Scribed by Roizen, Nancy J.


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
122 KB
Volume
9
Category
Article
ISSN
1080-4013

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✦ Synopsis


Abstract

Nongenetic as well as genetic etiologies must be explored in the child with identified hearing loss. Graduates of the neonatal intensive care unit are at increased risk for developing hearing loss due to hypoxia, hyperbilirubinemia, very low birth weight, and ototoxic medications. Although meningitis has decreased in frequency, it is still a risk factor for hearing loss. Cytomegalovirus remains the most common congenital infection and a relatively common etiology of hearing loss, which can be progressive. Preventable causes of hearing loss include those caused by head trauma, noise, and ototoxic medications. Identification of the etiology of hearing loss can facilitate the development of a treatment and management plan. MRDD Research Reviews 2003;9:120–127. Β© 2003 Wiley‐Liss, Inc.


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## Abstract Nonsyndromic autosomal dominant sensorineural hearing loss (SNHL) at the DFNA10 locus was described in two families in 2001. Causative mutations that affect the EyaHR domain of the β€˜Eyes absent 4’ (EYA4) protein were identified. We report on the clinical and genetic analyses of an Austr